Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 20/20 | 0.77 |
| ▸ | PDE4B | Q07343 | 20/20 | 0.77 |
| ▸ | PDE4C | Q08493 | 20/20 | 0.77 |
| ▸ | PDE4D | Q08499 | 20/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15754332 | 1.00 | PDE4A (0.77) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30362085 | 1.00 | PDE4A (0.77) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL15754542 | 0.94 | PDE4A (0.78) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL15754538 | 0.94 | PDE4A (0.78) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28391390 | 0.92 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28391387 | 0.92 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14799140 | 0.91 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL14799182 | 0.91 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL15754735 | 0.91 | PDE4A (0.77) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL15753798 | 0.90 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944612-B2 | 1-phenyl-2-pyridinyl alkyl alcohol derivatives as phosphodiesterase inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2018-04-17 | — | — | US | disclosed |
| EP-2928869-A1 | 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOL DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2015-10-14 | — | — | EP | disclosed |
| WO-2014086865-A1 | 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOL DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-06-12 | — | — | WO | disclosed |
| US-20140155391-A1 | 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOL DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140155391-A1 | 1-PHENYL-2-PYRIDINYL ALKYL ALCOHOL DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | PDE4A, PDE4B, PDE3A | PDE4A 1/4885PDE4B 2/4885PDE4C 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.