Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.46 |
| ▸ | AKT1 | P31749 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15754793 | 0.79 | ACKR3 (0.46) | AKT1ACKR3 | |
| SCHEMBL15754795 | 0.79 | ACKR3 (0.46) | AKT1ACKR3 | |
| SCHEMBL17206756 | 0.79 | ACKR3 (0.46) | AKT1ACKR3 | |
| SCHEMBL15760241 | 0.78 | HRH4 (0.46) | HRH4AKT1HRH3ACKR3IRAK1 | |
| SCHEMBL15758719 | 0.78 | HRH4 (0.46) | HRH4AKT1HRH3ACKR3IRAK1 | |
| Hydrochloric Acid SCHEMBL15754900 | 0.77 | ACKR3 (0.46) | AKT1ACKR3 | |
| Hydrochloric Acid SCHEMBL15754947 | 0.77 | ACKR3 (0.46) | AKT1ACKR3 | |
| Hydrochloric Acid SCHEMBL15754495 | 0.77 | ACKR3 (0.46) | AKT1ACKR3 | |
| Hydrochloric Acid SCHEMBL15754590 | 0.77 | ACKR3 (0.46) | AKT1ACKR3 | |
| Hydrochloric Acid SCHEMBL15754734 | 0.77 | ACKR3 (0.46) | AKT1ACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140154179-A1 | CXCR7 ANTAGONISTS | CHEMOCENTRYX, INC. (US) | 2014-06-05 | — | — | US | disclosed |
| US-20140154179-A1 | CXCR7 ANTAGONISTS | CHEMOCENTRYX, INC. (US) | 2014-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140154179-A1 | CXCR7 ANTAGONISTS | CXCR1, CXCR5, CCR7 | HRH4 247/4885AKT1 1223/4885HTR2C 865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.