Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PTPRC | P08575 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29187110 | 0.86 | CYP2D6 (0.45) | CYP2D6CA2CA1CA7CTSK | |
| SCHEMBL26326814 | 0.86 | CYP2D6 (0.45) | CYP2D6CA2CA1CA7CTSK | |
| SCHEMBL15781990 | 0.86 | CYP2D6 (0.44) | CYP2D6CA2CA1CA7CTSK | |
| SCHEMBL181731 | 0.83 | CYP2D6 (0.43) | CYP2D6CA2CA1CA7CTSK | |
| SCHEMBL20346816 | 0.79 | CYP2D6 (0.41) | CYP2D6CA2CA1CA7CTSK | |
| SCHEMBL17293179 | 0.79 | CYP2D6 (0.41) | CYP2D6CA2CA1CA7CTSK | |
| SCHEMBL17293181 | 0.79 | CYP2D6 (0.41) | CYP2D6CA2CA1CA7CTSK | |
| SCHEMBL18787618 | 0.79 | CYP2D6 (0.41) | CYP2D6CA2CA1CA7CTSK | |
| SCHEMBL14421548 | 0.78 | MGAM (0.46) | CA7MEN1GAAKMT2ACA12 | |
| SCHEMBL13542719 | 0.78 | CYP2D6 (0.40) | CYP2D6CA2CA1CA7CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140155469-A1 | ADENO-ASSOCIATED-VIRUS REP SEQUENCES, VECTORS AND VIRUSES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 2014-06-05 | — | — | US | disclosed |