Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.77 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.53 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | GNPAT | O15228 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15739372 | 0.87 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL15739351 | 0.87 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL1741931 | 0.87 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL2450656 | 0.87 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL2450650 | 0.87 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL4669761 | 0.87 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL15739333 | 0.87 | FOLH1 (1.00) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL2375284 | 0.86 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLAGAACA1 | |
| SCHEMBL12291002 | 0.86 | FOLH1 (0.69) | FOLH1NAALAD2RIMKLAGAACA1 | |
| SCHEMBL19352015 | 0.85 | FOLH1 (0.97) | FOLH1NAALAD2RIMKLASLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014085575-A1 | METHODS FOR TREATING CANCER USING COMBINATION THERAPIES | ENDOCYTE, INC. (US) | 2014-06-05 | — | — | WO | disclosed |
| US-20140154702-A1 | Methods For Treating Cancer Using Combination Therapies | ENDOCYTE INC (US) | 2014-06-05 | — | — | US | disclosed |