Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6916062 | 0.89 | PDE10A (0.83) | PDE10A | |
| SCHEMBL15768108 | 0.86 | PDE10A (0.59) | PDE10A | |
| SCHEMBL2385774 | 0.85 | PDE10A (0.69) | PDE10A | |
| SCHEMBL2384173 | 0.85 | PDE10A (0.68) | PDE10A | |
| SCHEMBL12316451 | 0.84 | PDE10A (0.67) | PDE10A | |
| SCHEMBL2401366 | 0.82 | PDE10A (0.64) | PDE10A | |
| SCHEMBL2373731 | 0.81 | PDE10A (1.00) | PDE10A | |
| SCHEMBL6915732 | 0.81 | PDE10A (0.78) | PDE10A | |
| SCHEMBL2395207 | 0.81 | PDE10A (0.65) | PDE10A | |
| SCHEMBL12266628 | 0.80 | PDE10A (0.85) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2552918-B1 | N-(IMIDAZOPYRIMIDIN-7-YL)-HETEROARYLAMIDE DERIVATIVES AND THEIR USE AS PDE10A INHIBITORS | HOFFMANN LA ROCHE (CH) | 2014-06-11 | — | — | EP | claimed |