Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 17/20 | 1.00 |
| ▸ | TNKS2 | Q9H2K2 | 17/20 | 1.00 |
| ▸ | PARP2 | Q9UGN5 | 9/20 | 1.00 |
| ▸ | PARP1 | P09874 | 8/20 | 0.79 |
| ▸ | GUSB | P08236 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15775361 | 0.88 | TNKS (1.00) | TNKSTNKS2PARP2PARP1 | |
| SCHEMBL165829 | 0.88 | TNKS (1.00) | TNKSTNKS2PARP2PARP1 | |
| SCHEMBL7568249 | 0.88 | TNKS (1.00) | TNKSTNKS2PARP2PARP1GUSB | |
| SCHEMBL1387257 | 0.88 | TNKS (1.00) | TNKSTNKS2PARP2PARP1GUSB | |
| SCHEMBL15775274 | 0.87 | TNKS (1.00) | TNKSTNKS2PARP2PARP1 | |
| SCHEMBL11102850 | 0.87 | TNKS (0.79) | TNKSTNKS2PARP2PARP1GUSB | |
| SCHEMBL15775410 | 0.87 | TNKS (1.00) | TNKSTNKS2PARP2PARP1 | |
| Hydrochloric Acid SCHEMBL28060794 | 0.87 | TNKS (0.97) | TNKSTNKS2PARP2PARP1 | |
| SCHEMBL7570159 | 0.84 | TNKS (0.73) | TNKSTNKS2PARP2PARP1 | |
| SCHEMBL7570390 | 0.84 | TNKS (1.00) | TNKSTNKS2PARP2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |