Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15776266 | 0.87 | PARP1 (0.69) | TNKSPARP1 | |
| SCHEMBL31014299 | 0.84 | PARP1 (0.67) | TNKSPARP1 | |
| SCHEMBL15775395 | 0.84 | PARP1 (0.67) | TNKSPARP1 | |
| Bromide SCHEMBL15775611 | 0.81 | PARP1 (0.74) | TNKSPARP1 | |
| SCHEMBL15569241 | 0.80 | PARP1 (0.73) | TNKSPARP1 | |
| SCHEMBL15775954 | 0.79 | TNKS (0.52) | TNKSPARP1 | |
| SCHEMBL17829653 | 0.78 | TNKS (0.59) | TNKSPARP1 | |
| SCHEMBL15775412 | 0.78 | TNKS (0.65) | TNKSPARP1 | |
| SCHEMBL15775237 | 0.78 | TNKS (0.61) | TNKSPARP1 | |
| SCHEMBL6644354 | 0.77 | TNKS (0.49) | TNKSPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014087165-A1 | TANKYRASE INHIBITORS | UNIVERSITY OF BATH (GB) | 2014-06-12 | — | — | WO | disclosed |