Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 19/20 | 0.38 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15793381 | 1.00 | ACACB (0.38) | ACACBDGAT2 | |
| SCHEMBL15794132 | 1.00 | ACACB (0.38) | ACACBDGAT2 | |
| SCHEMBL15793892 | 1.00 | ACACB (0.38) | ACACBDGAT2 | |
| SCHEMBL15794283 | 1.00 | ACACB (0.38) | ACACBDGAT2 | |
| SCHEMBL14814694 | 0.95 | ACACB (0.39) | ACACB | |
| SCHEMBL15793579 | 0.84 | ACACB (0.37) | ACACB | |
| SCHEMBL15794243 | 0.84 | ACACB (0.37) | ACACB | |
| SCHEMBL15793932 | 0.84 | ACACB (0.37) | ACACB | |
| SCHEMBL15798562 | 0.84 | ACACB (0.37) | ACACB | |
| SCHEMBL15793943 | 0.84 | ACACB (0.37) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931727-A1 | DIAZEPINE DERIVATIVES USEFUL AS CALCIUM CHANNEL BLOCKERS IN THE TREATMENT OF PAIN | Abbvie Inc. (US) | 2015-10-21 | — | — | EP | disclosed |
| WO-2014093337-A1 | DIAZEPINE DERIVATIVES USEFUL AS CALCIUM CHANNEL BLOCKERS IN THE TREATMENT OF PAIN | ABBVIE, INC. (US) | 2014-06-19 | — | — | WO | disclosed |