Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 16/20 | 0.49 |
| ▸ | HTR2B | P41595 | 14/20 | 0.49 |
| ▸ | HTR2A | P28223 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL337619 | 0.89 | HTR2C (0.51) | HTR2CHTR2BHTR2A | |
| SCHEMBL337591 | 0.89 | HTR2C (0.51) | HTR2CHTR2BHTR2A | |
| SCHEMBL337382 | 0.89 | HTR2C (0.51) | HTR2CHTR2BHTR2A | |
| SCHEMBL24710626 | 0.87 | HTR2C (0.41) | HTR2CHTR2BHTR2A | |
| SCHEMBL7888297 | 0.87 | HTR2C (0.41) | HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL14816152 | 0.87 | HTR2C (0.50) | HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL23124413 | 0.87 | HTR2C (0.50) | HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL9940935 | 0.87 | HTR2C (0.50) | HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL3709561 | 0.86 | HTR2C (0.40) | HTR2CHTR2BHTR2A | |
| Hydrochloric Acid SCHEMBL3712796 | 0.86 | HTR2C (0.40) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900672-B1 | BET-PROTEIN INHIBITORY 5-ARYL-TRIAZOLO-AZEPINES | Bayer Pharma AG (DE) | 2017-02-22 | — | — | EP | disclosed |
| EP-2931727-A1 | DIAZEPINE DERIVATIVES USEFUL AS CALCIUM CHANNEL BLOCKERS IN THE TREATMENT OF PAIN | Abbvie Inc. (US) | 2015-10-21 | — | — | EP | disclosed |
| WO-2014093337-A1 | DIAZEPINE DERIVATIVES USEFUL AS CALCIUM CHANNEL BLOCKERS IN THE TREATMENT OF PAIN | ABBVIE, INC. (US) | 2014-06-19 | — | — | WO | disclosed |