Tyrosine

Tyrosine

SCHEMBL1580

NC(Cc1ccc(O)cc1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC7A5 Q01650 3/20 1.00
▸ PTGS1 P23219 3/20 0.70
▸ ALPI P09923 1/20 0.70
▸ PKM P14618 1/20 0.70
▸ XIAP P98170 1/20 0.70
▸ ALOX15 P16050 3/20 0.65
▸ HIF1A Q16665 3/20 0.65
▸ KDM4E B2RXH2 2/20 0.65
▸ TDP1 Q9NUW8 2/20 0.65
▸ USP2 O75604 1/20 0.65
▸ EGFR P00533 1/20 0.65
▸ LCK P06239 1/20 0.65
▸ FYN P06241 1/20 0.65
▸ ADORA3 P0DMS8 1/20 0.65
▸ HTR2A P28223 1/20 0.65
▸ PTGS2 P35354 1/20 0.65
▸ RECQL P46063 1/20 0.65
▸ HSD17B10 Q99714 1/20 0.65
▸ TPH1 P17752 1/20 0.59
▸ GRB2 P62993 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL11676395 1.00 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL11520027 1.00 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL10978820 1.00 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL1581 1.00 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL20787 1.00 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL638520 1.00 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL11676367 1.00 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL10978805 1.00 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL11520041 1.00 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL30081492 1.00 SLC7A5 (1.00) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 721385 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9976074-B2 Self-suspending proppant particulates using canola protein-based hydrogel HALLIBURTON ENERGY SERVICES, INC. (US) 2018-05-22 — — US claimed
US-9974851-B2 Human rotavirus vaccine strains and diagnostics THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2018-05-22 — — US claimed
US-9975914-B2 Antimicrobial preparation and uses thereof Akeso Biomedical, Inc. (US) 2018-05-22 — — US claimed
US-9976126-B2 Modified glycine oxidase AJINOMOTO CO., INC. (JP) 2018-05-22 — — US claimed
WO-2018089269-A1 NOVEL CLASS OF QUINOLONE HETEROCYCLIC AROMATIC MOLECULES FOR CANCER TREATMENT RENOTARGET THERAPEUTICS INC. (US) 2018-05-17 — — WO claimed
WO-2018086732-A1 COSMETIC FORMULATIONS FOR TOPICAL APPLICATIONS CONTAINING ERYTHROPOIETIN-DERIVED MOLECULES ASC REGENITY LTD. (GB) 2018-05-17 — — WO claimed
US-20180135061-A1 METHODS OF MODULATING mRNA STABILITY AND PROTEIN EXPRESSION UNIV CASE WESTERN RESERVE (US) 2018-05-17 — — US claimed
US-20180134810-A1 URANIUM-CHELATING PEPTIDES AND USES THEREOF COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2018-05-17 — — US claimed
US-20180135074-A1 RECOMBINANT AAV VECTORS FOR GENE THERAPY OF HUMAN HEMATOPOIETIC DISORDERS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2018-05-17 — — US claimed
US-20180134719-A1 SUBSTITUTED N-(3-(PYRIMIDIN-4-YL)PHENYL)ACRYLAMIDE ANALOGS AS TYROSINE RECEPTOR KINASE BTK INHIBITORS UNIVERSITY OF UTAH RESEARCH FOUNDATION 2018-05-17 — — US claimed
US-3972918-A Process for separating DOPA from tyrosine THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1976-08-03 — — US claimed
US-3971737-A [2-Methyl-Ala6 ]LRH AMERICAN HOME PRODUCTS CORPORATION (US) 1976-07-27 — — US claimed
US-3963697-A Labelled cardiotonic glycosides for use in radioimmunoassay CURTIS NUCLEAR CORPORATION (US) 1976-06-15 — — US claimed
US-3953416-A Synthetic decapeptide having the activity of the luteinizing hormone releasing hormone and method for manufacturing the same FOLKERS KARL 1976-04-27 — — US claimed
US-3950529-A NUTRIENT SOLUTION FOR INTRAVENOUS ADMINISTRATION MASSACHUSETTS GENERAL HOSPITAL (US) 1976-04-13 — — US claimed
US-3943038-A Method for producing amino acids by culturing hydrogen-oxidizing bacteria AJINOMOTO CO., INC. (JA) 1976-03-09 — — US claimed
US-3941763-A POLYPEPTIDE AMERICAN HOME PRODUCTS CORPORATION (US) 1976-03-02 — — US claimed
US-3940380-A P-Glu-D-Phe-Trp-Ser-Tyr-2-Me.Ala-Leu-Arg-Pro-NH2 and intermediates AMERICAN HOME PRODUCTS CORPORATION (US) 1976-02-24 — — US claimed
US-3933782-A (N-Acetyl)-Pro-D-Phe-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt and intermediates AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-20 — — US claimed
US-3930948-A ENZYMATIC METHOD FOR PRODUCING AROMATIC ETHYLAMINES AJINOMOTO CO., INC. (JA) 1976-01-06 — — US claimed
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