Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 7/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 7/20 | 0.40 |
| ▸ | CTSK | P43235 | 6/20 | 0.40 |
| ▸ | CTSL | P07711 | 4/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1580818 | 0.89 | F2R (0.56) | F2RCNR1TMEM97EPHX2PKM | |
| SCHEMBL1580561 | 0.88 | F2R (0.60) | F2REPHX2PKMTACR1AKR1C3 | |
| SCHEMBL1580852 | 0.86 | F2R (0.48) | F2RCNR1TMEM97EPHX2TACR1 | |
| SCHEMBL642020 | 0.85 | F2R (0.53) | F2RCNR1TMEM97EPHX2PKM | |
| SCHEMBL1580358 | 0.85 | F2R (0.75) | F2R | |
| SCHEMBL9895351 | 0.84 | F2R (0.51) | F2RCNR1TMEM97EPHX2PKM | |
| SCHEMBL1580620 | 0.82 | F2R (0.55) | F2RPKMAKR1C3 | |
| SCHEMBL9895349 | 0.82 | F2R (0.51) | F2RCNR1TMEM97EPHX2PKM | |
| SCHEMBL1580812 | 0.81 | F2R (0.54) | F2RAKR1C3 | |
| SCHEMBL641910 | 0.81 | F2R (0.47) | F2RCNR1TMEM97EPHX2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227466-B1 | HETEROARYL-SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AG (DE) | 2011-04-20 | — | — | EP | disclosed |
| EP-2227466-A2 | HETEROARYL-SUBSTITUTED PIPERIDINES | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-09-15 | — | — | EP | disclosed |
| WO-2009068214-A2 | HETEROARYL-SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-06-04 | — | — | WO | disclosed |