Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 7/20 | 0.66 |
| ▸ | P2RY2 | P41231 | 16/20 | 0.59 |
| ▸ | P2RY4 | P51582 | 9/20 | 0.59 |
| ▸ | POLA1 | P09884 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15828307 | 1.00 | P2RY6 (0.66) | P2RY6P2RY2P2RY4POLA1 | |
| SCHEMBL15813164 | 1.00 | P2RY6 (0.66) | P2RY6P2RY2P2RY4POLA1 | |
| SCHEMBL21345114 | 0.98 | P2RY6 (0.68) | P2RY6P2RY2P2RY4POLA1 | |
| SCHEMBL23897983 | 0.92 | P2RY6 (0.63) | P2RY6P2RY2P2RY4POLA1 | |
| SCHEMBL16144255 | 0.91 | P2RY6 (0.60) | P2RY6P2RY2P2RY4POLA1 | |
| SCHEMBL23897738 | 0.90 | P2RY2 (0.61) | P2RY6P2RY2P2RY4POLA1 | |
| SCHEMBL23898181 | 0.90 | P2RY2 (0.59) | P2RY6P2RY2P2RY4POLA1 | |
| SCHEMBL21345754 | 0.90 | P2RY6 (0.56) | P2RY6P2RY2P2RY4 | |
| SCHEMBL23897804 | 0.88 | P2RY2 (0.58) | P2RY6P2RY2P2RY4POLA1 | |
| SCHEMBL23897567 | 0.88 | P2RY6 (0.56) | P2RY6P2RY2P2RY4POLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935304-A1 | 4'-FLUORO NUCLEOSIDES FOR THE TREATMENT OF HCV | IDENIX Pharmaceuticals, Inc. (US) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014099941-A1 | 4'-FLUORO NUCLEOSIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS, INC. (US) | 2014-06-26 | — | — | WO | disclosed |