SCHEMBL15823328

SCHEMBL15823328

FC(F)(F)COCCCCCCCCCCCCCCCOCC(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CES1 P23141 1/20 0.46
PLA2G2C Q5R387 1/20 0.41
EPHX2 P34913 1/20 0.38
CES2 O00748 1/20 0.37
CYP2C9 P11712 1/20 0.35
TSHR P16473 1/20 0.35
CYP2C19 P33261 1/20 0.35
HIF1A Q16665 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9076724 0.90 CES1 (0.38) CES1PLA2G2CEPHX2CA1CA2
SCHEMBL124511 0.87 CES1 (0.39) CES1PLA2G2CEPHX2CES2CYP2C9
SCHEMBL16288545 0.87 CES1 (0.39) CES1PLA2G2CEPHX2CES2CYP2C9
SCHEMBL16288356 0.87 CES1 (0.39) CES1PLA2G2CEPHX2CES2CYP2C9
SCHEMBL16288749 0.87 CES1 (0.39) CES1PLA2G2CEPHX2CES2CYP2C9
SCHEMBL19043522 0.87 CES1 (0.64) CES1PLA2G2CCES2CYP2C9TSHR
SCHEMBL16263365 0.87 CES1 (0.44) CES1PLA2G2CEPHX2CES2CYP2C9
SCHEMBL128963 0.87 CES1 (0.64) CES1PLA2G2CCES2CYP2C9TSHR
SCHEMBL16263366 0.87 CES1 (0.44) CES1PLA2G2CEPHX2CES2CYP2C9
SCHEMBL16288954 0.87 CES1 (0.39) CES1PLA2G2CEPHX2CES2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2935185-A1 (6R,10R)-6,10,14-TRIMETYLPENTADECAN-2-ONE PREPARED FROM 6,10,14-TRIMETYLPENTADECA-5,9,13-TRIEN-2-ONE OR 6,10,14-TRIMETYLPENTADECA-5,9-DIEN-2-ONE DSM IP Assets B.V. (NL) 2015-10-28 EP disclosed
WO-2014096098-A1 (6R,10R)-6,10,14-TRIMETYLPENTADECAN-2-ONE PREPARED FROM 6,10,14-TRIMETYLPENTADECA-5,9,13-TRIEN-2-ONE OR 6,10,14-TRIMETYLPENTADECA-5,9-DIEN-2-ONE DSM IP ASSETS B.V. (NL) 2014-06-26 WO disclosed