Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 4/20 | 0.34 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | LAP3 | P28838 | 2/20 | 0.31 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1582657 | 0.98 | CTSC (0.40) | CTSCANPEPMMP1MMP2MMP3 | |
| SCHEMBL1582304 | 0.89 | CTSC (0.34) | CTSCANPEP | |
| SCHEMBL1582592 | 0.87 | CTSC (0.46) | CTSCANPEPMMP1MMP2MMP3 | |
| SCHEMBL11307612 | 0.81 | ANPEP (0.32) | ANPEPMMP1MMP2MMP3CA12 | |
| SCHEMBL11296860 | 0.79 | ANPEP (0.32) | ANPEPMMP1MMP2MMP3 | |
| SCHEMBL11297087 | 0.79 | METAP1 (0.38) | CTSCCA2 | |
| SCHEMBL11299128 | 0.78 | DPP4 (0.42) | ANPEPMMP1MMP2CA12CA1 | |
| SCHEMBL18919534 | 0.78 | DPP4 (0.42) | ANPEPMMP1MMP2CA12CA1 | |
| SCHEMBL1582242 | 0.78 | DPP4 (0.42) | ANPEPMMP1MMP2CA12CA1 | |
| SCHEMBL1582769 | 0.78 | DPP4 (0.42) | ANPEPMMP1MMP2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325024-B1 | SELECTIVE GROWTH MEDIA | NEWCASTLE UPON TYNE HOSPITALS NAT HEALTH SERVICE TRUST (GB) | 2011-04-20 | — | — | EP | disclosed |
| US-4250085-A | PHOSPHONATE-CONTAINING OLIGOPEPTIDES, BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 1981-02-10 | — | — | US | disclosed |
| US-4134972-A | OLIGOPEPTIDES | HOFFMANN-LA ROCHE INC. (US) | 1979-01-16 | — | — | US | disclosed |
| US-4127649-A | PEPTIDES | HOFFMANN-LA ROCHE INC. (US) | 1978-11-28 | — | — | US | disclosed |
| US-4100275-A | PEPTIDES | HOFFMANN-LA ROCHE INC. (US) | 1978-07-11 | — | — | US | disclosed |