Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15823835 | 1.00 | PIK3CB (0.37) | PIK3CBRECQLTP53SIGMAR1RAB9A | |
| SCHEMBL15823838 | 1.00 | PIK3CB (0.37) | PIK3CBRECQLTP53SIGMAR1RAB9A | |
| SCHEMBL15822599 | 0.92 | TP53 (0.38) | PIK3CBRECQLTP53SIGMAR1RAB9A | |
| SCHEMBL15822602 | 0.92 | TP53 (0.38) | PIK3CBRECQLTP53SIGMAR1RAB9A | |
| SCHEMBL15822603 | 0.92 | TP53 (0.38) | PIK3CBRECQLTP53SIGMAR1RAB9A | |
| SCHEMBL15822931 | 0.90 | PIK3CB (0.39) | PIK3CBRECQLTP53SIGMAR1MAPT | |
| SCHEMBL15822935 | 0.90 | PIK3CB (0.39) | PIK3CBRECQLTP53SIGMAR1MAPT | |
| SCHEMBL15822472 | 0.86 | PIK3CB (0.38) | PIK3CBRECQLTP53SIGMAR1MAPT | |
| SCHEMBL15822469 | 0.86 | PIK3CB (0.38) | PIK3CBRECQLTP53SIGMAR1MAPT | |
| SCHEMBL15823566 | 0.85 | PIK3CB (0.38) | PIK3CBRECQLTP53SIGMAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2934594-A1 | NEW CYCLOHEXYL AND QUINUCLIDINYL CARBAMATE DERIVATIVES HAVING BETA2 ADRENERGIC AGONIST AND M3 MUSCARINIC ANTAGONIST ACTIVITY | Almirall, S.A. (ES) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014095920-A1 | NEW CYCLOHEXYL AND QUINUCLIDINYL CARBAMATE DERIVATIVES HAVING BETA2 ADRENERGIC AGONIST AND M3 MUSCARINIC ANTAGONIST ACTIVITY | ALMIRALL, S.A. (ES) | 2014-06-26 | — | — | WO | disclosed |