SCHEMBL1582516

SCHEMBL1582516

CC(C)C[C@H](N)C(=O)N(CP(=O)(O)O)C(=O)[C@H](C)N

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ LAP3 P28838 8/20 0.44
▸ ANPEP P15144 7/20 0.44
▸ ERAP1 Q9NZ08 1/20 0.44
▸ SLC7A5 Q01650 1/20 0.41
▸ SLC1A3 P43003 2/20 0.37
▸ SLC1A2 P43004 2/20 0.37
▸ RNPEP Q9H4A4 2/20 0.33
▸ DNPEP Q9ULA0 1/20 0.33
▸ SLC1A1 P43005 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1582150 0.88 ANPEP (0.40) LAP3ANPEPERAP1
SCHEMBL1582673 0.75 ANPEP (0.49) LAP3ANPEPSLC7A5SLC1A3SLC1A2
SCHEMBL18774977 0.69 SLC7A5 (0.52) LAP3ANPEPERAP1SLC7A5SLC1A3
SCHEMBL1911122 0.68 SLC7A5 (0.56) LAP3ANPEPERAP1SLC7A5SLC1A3
SCHEMBL4594704 0.68 SLC7A5 (0.56) LAP3ANPEPERAP1SLC7A5SLC1A3
SCHEMBL4595827 0.68 SLC7A5 (0.56) LAP3ANPEPERAP1SLC7A5SLC1A3
SCHEMBL2322429 0.67 SLC7A5 (0.46) LAP3ANPEPSLC7A5SLC1A3SLC1A2
Hydrochloric Acid SCHEMBL56160 0.66 SLC7A5 (0.54) LAP3ANPEPERAP1SLC7A5SLC1A3
Hydrochloric Acid SCHEMBL3223338 0.66 SLC7A5 (0.54) LAP3ANPEPERAP1SLC7A5SLC1A3
Leucine SCHEMBL3720251 0.66 SLC7A5 (0.82) LAP3ANPEPERAP1SLC7A5SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1325024-B1 SELECTIVE GROWTH MEDIA NEWCASTLE UPON TYNE HOSPITALS NAT HEALTH SERVICE TRUST (GB) 2011-04-20 — — EP disclosed
EP-1325024-A1 SELECTIVE GROWTH MEDIA The Newcastle upon Tyne Hospitals National Health Service Trust (GB) 2003-07-09 — — EP disclosed
WO-2002024725-A1 SELECTIVE GROWTH MEDIA NEWCASTLE UPON TYNE HOSPITALS NHS TRUST (GB) 2002-03-28 — — WO disclosed
US-4134972-A OLIGOPEPTIDES HOFFMANN-LA ROCHE INC. (US) 1979-01-16 — — US disclosed
US-4127649-A PEPTIDES HOFFMANN-LA ROCHE INC. (US) 1978-11-28 — — US disclosed
US-4100275-A PEPTIDES HOFFMANN-LA ROCHE INC. (US) 1978-07-11 — — US disclosed
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