SCHEMBL15825344

SCHEMBL15825344

CC(O)C(N)c1cc[nH]n1

nearest known ligand 0.34

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SCN10A Q9Y5Y9 5/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL542127 0.79
SCHEMBL25078495 0.79
SCHEMBL1369329 0.79
SCHEMBL19514367 0.79
SCHEMBL2633391 0.79
Hydrochloric Acid SCHEMBL10959828 0.77
SCHEMBL1762925 0.75
SCHEMBL28881697 0.73
SCHEMBL23015487 0.73
SCHEMBL9988508 0.71 EPHX1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2935240-A1 PRMT5 INHIBITORS AND USES THEREOF Epizyme, Inc. (US) 2015-10-28 EP disclosed
WO-2014100695-A1 PRMT5 INHIBITORS AND USES THEREOF Epizyme, Inc. (US) 2014-06-26 WO disclosed