Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 3/20 | 0.54 |
| ▸ | CDK2 | P24941 | 3/20 | 0.54 |
| ▸ | IGF1R | P08069 | 13/20 | 0.52 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12783910 | 0.91 | CCNA2 (0.54) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL15827556 | 0.89 | NTRK1 (0.54) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL2069684 | 0.83 | NTRK1 (0.54) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL12784848 | 0.83 | CCNA2 (0.67) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL1164939 | 0.83 | NTRK1 (0.54) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL15809733 | 0.83 | NTRK1 (0.54) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL12784666 | 0.82 | CCNA2 (0.51) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL15827606 | 0.82 | CCNA2 (0.54) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL1164495 | 0.82 | CCNA2 (0.80) | CCNA2CDK2IGF1RNTRK1 | |
| SCHEMBL1164225 | 0.82 | IGF1R (0.57) | CCNA2CDK2IGF1RNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2464641-B1 | PYRIMIDINE COMPOUNDS AS TUBERCULOSIS INHIBITORS | VERTEX PHARMA (US) | 2014-06-25 | — | — | EP | disclosed |