SCHEMBL158279

SCHEMBL158279

Nc1ccc(Cl)cc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29732941 1.00
Hydrochloric Acid SCHEMBL4374970 0.97 TSHR (0.94)
Hydrochloric Acid SCHEMBL8895098 0.97 TSHR (0.94)
Nitrogen SCHEMBL4346621 0.95 TSHR (0.90)
SCHEMBL9082347 0.90 TSHR (0.81)
SCHEMBL28200927 0.88 CYP3A4 (0.77)
Acetonitrile SCHEMBL9412155 0.86 CYP3A4 (0.74)
Formic Acid SCHEMBL27621713 0.86 TSHR (0.74)
Nitrogen SCHEMBL28997928 0.84 TSHR (0.71)
Hydrochloric Acid SCHEMBL29274500 0.84 TSHR (0.71)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2929 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094941-A Novel azido formation of 6-hydroxy-benzomorpholine (3, 4-dihydro-2H-1, 4-benzoxazin-6-ol) 2026-05-26 CN claimed
WO-2025099111-A1 NEW TELESCOPING SYNTHESES OF 6-HYDROXY-BENZOMORPHOLINE (3,4-DIHYDRO-2H-1,4-BENZOXAZIN-6-OL) WELLA GERMANY GMBH (DE) 2025-05-15 WO claimed
CN-119823953-A Mutant based on cytochrome P450BM3 and application thereof in chloroaniline biodegradation 中国水产科学研究院黄海水产研究所 2025-04-15 CN claimed
CN-119707773-A Preparation method and application of maleimide structure-containing compound 中国农业大学 2025-03-28 CN claimed
WO-2025056077-A1 SURFACE-MODIFIED OXIDE SOLID ELECTROLYTE POWDER, COMPOSITE SOLID ELECTROLYTE, AND PREPARATION METHOD THEREFOR 有研稀土高技术有限公司 2025-03-20 WO claimed
CN-119591505-A 2-Chlorophenylhydrazine hydrochloride and preparation process thereof 白银星宇生物科技有限公司 2025-03-11 CN claimed
CN-119552183-A Narrow emission compound based on spirobifluorene and electroluminescent device prepared from narrow emission compound 中国科学院宁波材料技术与工程研究所 2025-03-04 CN claimed
CN-119431238-A Aluminum ion detection reagent and preparation method and application thereof 河南省氟基新材料科技有限公司 2025-02-14 CN claimed
CN-119219514-A Synthesis method of N- (2, 4-dichloro-5-nitrophenyl) acetamide 浙大宁波理工学院 2024-12-31 CN claimed
CN-119143750-A Preparation method of N-ortho-alkyl substituted 1, 10-phenanthroline compound and catalyst prepared by same 中国石油化工股份有限公司 2024-12-17 CN claimed
US-4310619-A LIGHT SENSITIVE ELEMENT COMPRISING A 5-PYRAZOLONE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1982-01-12 US claimed
US-4310623-A THIO-PYRAZOLINE COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1982-01-12 US claimed
US-4308343-A MAGENTA 2-EQUIVALENT COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1981-12-29 US claimed
US-4301235-A A PYRAZOLONE MAGENTA COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1981-11-17 US claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
US-4264723-A CONTAINING PYRAZOLONE COUPLERS FUJI PHOTO FILM CO., LTD. (JP) 1981-04-28 US claimed
EP-0025166-A1 Process for preparing vat dyestuffs of the anthraquinone series, their use in dyeing and printing preparations and in dyeing and printing CIBA-GEIGY AG (CH) 1981-03-18 EP claimed
US-4190419-A Device for detecting serum bilirubin MILES LABORATORIES, INC. (US) 1980-02-26 US claimed
US-3991044-A Process for improving lightfastness of an azo pigment by heat treatment HERCULES INCORPORATED (US) 1976-11-09 US claimed
US-3979377-A Yellow azo pigment and process of preparation from dichloroaniline and barbituric acid E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-09-07 US claimed