Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 11/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RARA | P10276 | 2/20 | 0.50 |
| ▸ | RARG | P13631 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | TACR2 | P21452 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16807155 | 0.99 | RARB (0.53) | RARBALDH1A1RARARARGMEN1 | |
| SCHEMBL16807147 | 0.95 | RARB (0.50) | RARBALDH1A1RARARARGMEN1 | |
| SCHEMBL16807150 | 0.94 | RARB (0.51) | RARBALDH1A1RARARARGMEN1 | |
| SCHEMBL16807077 | 0.94 | RARB (0.51) | RARBALDH1A1RARARARGMEN1 | |
| SCHEMBL16807151 | 0.94 | RARB (0.51) | RARBALDH1A1RARARARGMEN1 | |
| SCHEMBL16807146 | 0.93 | RARB (0.53) | RARBALDH1A1RARARARGMEN1 | |
| SCHEMBL16807100 | 0.93 | RARB (0.53) | RARBALDH1A1RARARARGMEN1 | |
| SCHEMBL16807158 | 0.93 | RARB (0.53) | RARBALDH1A1RARARARGMEN1 | |
| SCHEMBL16807114 | 0.93 | RARB (0.50) | RARBALDH1A1RARARARGMEN1 | |
| SCHEMBL16807154 | 0.93 | RARB (0.53) | RARBALDH1A1RARARARGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2883934-B1 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2019-11-13 | — | — | EP | disclosed |
| EP-2883934-B1 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2019-11-13 | — | — | EP | disclosed |
| US-10131841-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2018-11-20 | — | — | US | disclosed |
| EP-2931838-B1 | LIQUID-CRYSTAL DISPLAYS AND LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2017-08-16 | — | — | EP | disclosed |
| EP-2931838-B1 | LIQUID-CRYSTAL DISPLAYS AND LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2017-08-16 | — | — | EP | disclosed |
| US-9726933-B2 | Liquid-crystal displays and liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2017-08-08 | — | — | US | disclosed |
| US-9726933-B2 | Liquid-crystal displays and liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2017-08-08 | — | — | US | disclosed |
| US-20150301368-A1 | Liquid-crystal displays and liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | disclosed |
| US-20150301368-A1 | Liquid-crystal displays and liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | disclosed |
| US-20150171372-A1 | FLUORESCENT MATERIAL, FLUORESCENT COATING MATERIAL, PHOSPHOR SUBSTRATE, ELECTRONIC APPARATUS, AND LED PACKAGE | SHARP KABUSHIKI KAISHA (JP) | 2015-06-18 | — | — | US | disclosed |
| US-20150166890-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-18 | — | — | US | disclosed |
| US-20150166890-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-18 | — | — | US | disclosed |
| US-20150166890-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-06-18 | — | — | US | disclosed |
| EP-2883934-A1 | Liquid-crystalline medium | Merck Patent GmbH (DE) | 2015-06-17 | — | — | EP | disclosed |
| EP-2883934-A1 | Liquid-crystalline medium | Merck Patent GmbH (DE) | 2015-06-17 | — | — | EP | disclosed |
| WO-2014094959-A1 | LIQUID-CRYSTAL DISPLAYS AND LIQUID-CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2014-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150301368-A1 | Liquid-crystal displays and liquid-crystalline media having homeotropic alignment | LASP1, VCL, NEFM | RARB 3014/4885ALDH1A1 4616/4885RARA 2798/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.