Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLG | P54098 | 2/20 | 0.51 |
| ▸ | PNP | P00491 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | FUT5 | Q11128 | 1/20 | 0.46 |
| ▸ | KRAS | P01116 | 2/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | POLA1 | P09884 | 1/20 | 0.44 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.44 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.44 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.43 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18877607 | 1.00 | POLG (0.51) | POLGPNPPOLBTGM2FUT5 | |
| SCHEMBL15837371 | 1.00 | POLG (0.51) | POLGPNPPOLBTGM2FUT5 | |
| SCHEMBL21015822 | 0.99 | PNP (0.50) | POLGPNPPOLBTGM2FUT5 | |
| SCHEMBL15833114 | 0.94 | POLG (0.51) | POLGPNPPOLBTGM2FUT5 | |
| SCHEMBL15837393 | 0.94 | POLG (0.51) | POLGPNPPOLBTGM2FUT5 | |
| SCHEMBL20693182 | 0.94 | POLG (0.51) | POLGPNPPOLBTGM2FUT5 | |
| SCHEMBL15833118 | 0.93 | NT5E (0.47) | POLGPNPPOLBTGM2FUT5 | |
| SCHEMBL18475060 | 0.93 | NT5E (0.47) | POLGPNPPOLBTGM2FUT5 | |
| SCHEMBL31228120 | 0.92 | POLG (0.49) | POLGPNPPOLBTGM2FUT5 | |
| SCHEMBL15837321 | 0.91 | POLG (0.42) | POLGPNPPOLBTGM2P2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015054465-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | ALIOS BIOPHARMA, INC. (US) | 2015-04-16 | — | — | WO | disclosed |
| WO-2014100505-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | ALIOS BIOPHARMA, INC. (US) | 2014-06-26 | — | — | WO | disclosed |