SCHEMBL15833746

SCHEMBL15833746

Clc1ccc(Oc2ccc(C3(Cn4cncn4)CCCCO3)c(Cl)c2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 15/20 0.52
CYP2C9 P11712 1/20 0.52
THRB P10828 1/20 0.48
LMNA P02545 2/20 0.41
FYN P06241 2/20 0.41
CYP51A1 Q16850 2/20 0.41
NR1I2 O75469 1/20 0.41
PGR P06401 1/20 0.41
HSP90AA1 P07900 1/20 0.41
CHRM2 P08172 1/20 0.41
CHRM4 P08173 1/20 0.41
CHRM5 P08912 1/20 0.41
ADRA2A P08913 1/20 0.41
CHRM1 P11229 1/20 0.41
TSHR P16473 1/20 0.41
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41
CHRM3 P20309 1/20 0.41
DRD1 P21728 1/20 0.41
TBXA2R P21731 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15823365 0.92 CYP3A4 (0.55) CYP3A4CYP2C9THRBLMNAFYN
SCHEMBL15822985 0.88 CYP3A4 (0.42) CYP3A4CYP2C9THRBLMNAFYN
SCHEMBL10594823 0.85 CYP3A4 (0.65) CYP3A4CYP2C9THRBLMNAFYN
SCHEMBL16282002 0.81 CYP3A4 (0.62) CYP3A4CYP2C9THRBLMNAFYN
SCHEMBL9854122 0.81 CYP3A4 (0.80) CYP3A4CYP2C9THRBLMNAFYN
SCHEMBL15822641 0.80 CYP3A4 (0.44) CYP3A4CYP2C9THRBLMNAFYN
SCHEMBL9854152 0.78 CYP3A4 (0.48) CYP3A4CYP2C9THRBLMNAFYN
SCHEMBL9854137 0.77 CYP3A4 (0.48) CYP3A4CYP2C9THRBLMNAFYN
SCHEMBL1280393 0.77 CYP3A4 (0.52) CYP3A4CYP2C9THRBLMNAFYN
SCHEMBL1279427 0.77 CYP3A4 (0.59) CYP3A4CYP2C9THRBLMNAFYN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014095534-A1 NEW SUBSTITUTED TRIAZOLES AND IMIDAZOLES AND THEIR USE AS FUNGICIDES BASF SE (DE) 2014-06-26 WO disclosed