Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 19/20 | 0.76 |
| ▸ | PDE4A | P27815 | 2/20 | 0.57 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1434490 | 0.86 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL885388 | 0.85 | PDE4D (0.93) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL885393 | 0.84 | PDE4D (0.81) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL885298 | 0.84 | PDE4D (0.81) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL1434081 | 0.84 | PDE4D (0.72) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL885255 | 0.84 | PDE4D (1.00) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL10193885 | 0.83 | PDE4D (0.81) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL1434331 | 0.83 | PDE4D (0.81) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL1434359 | 0.80 | PDE4D (0.74) | PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL1434482 | 0.79 | PDE4D (0.80) | PDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014096018-A1 | METHODS FOR THE PREPARATION OF SUBSTITUTED ACETOPHENONES | LEO PHARMA A/S (DK) | 2014-06-26 | — | — | WO | disclosed |