⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170292 | 0.78 | — | — | |
| Chloromethane SCHEMBL11675613 | 0.76 | — | — | |
| SCHEMBL6064258 | 0.69 | — | — | |
| SCHEMBL5140235 | 0.67 | — | — | |
| SCHEMBL6429784 | 0.67 | — | — | |
| SCHEMBL28958455 | 0.65 | — | — | |
| Water SCHEMBL28876243 | 0.65 | — | — | |
| SCHEMBL250606 | 0.65 | — | — | |
| SCHEMBL6270785 | 0.64 | — | — | |
| SCHEMBL3720815 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113024592-A | Synthetic method of azetidine silicon precursor compound and method for synthesizing six-membered silicon nitrogen heterocyclic compound by using same | 四川大学 | 2021-06-25 | — | — | CN | disclosed |
| EP-2488522-B1 | NOVEL METHOD FOR PREPARING ENTECAVIR AND INTERMEDIATE USED THEREIN | HANMI SCIENCE CO LTD (KR) | 2017-02-15 | — | — | EP | disclosed |
| US-8569491-B2 | Method for preparing entecavir and intermediate used therein | HANMI SCIENCE CO., LTD (KR) | 2013-10-29 | — | — | US | disclosed |
| EP-2488522-A2 | NOVEL METHOD FOR PREPARING ENTECAVIR AND INTERMEDIATE USED THEREIN | Hanmi Holdings Co., Ltd. (KR) | 2012-08-22 | — | — | EP | disclosed |
| US-20120202998-A1 | NOVEL METHOD FOR PREPARING ENTECAVIR AND INTERMEDIATE USED THEREIN | HANMI HOLDINGS CO., LTD. (KR) | 2012-08-09 | — | — | US | disclosed |
| WO-2011046303-A2 | NOVEL METHOD FOR PREPARING ENTECAVIR AND INTERMEDIATE USED THEREIN | HANMI HOLDINGS CO., LTD. (KR) | 2011-04-21 | — | — | WO | disclosed |