Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 6/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 3/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15843801 | 1.00 | TSHR (0.51) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL15843472 | 0.98 | TSHR (0.53) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL15864944 | 0.98 | TSHR (0.53) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL15843638 | 0.98 | TSHR (0.53) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL15843503 | 0.98 | TSHR (0.53) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL15843637 | 0.98 | TSHR (0.53) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL15843504 | 0.98 | TSHR (0.53) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL15843471 | 0.98 | TSHR (0.53) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL15843546 | 0.95 | TSHR (0.50) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL15843547 | 0.95 | TSHR (0.50) | TSHRTP53CYP3A4MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9315599-B2 | Functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2016-04-19 | — | — | US | claimed |
| US-20140187712-A1 | FUNCTIONALIZED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2014-07-03 | — | — | US | claimed |
| US-9315599-B2 | Functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2016-04-19 | — | — | US | disclosed |
| WO-2014107447-A1 | FUNCTIONALIZED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2014-07-10 | — | — | WO | disclosed |
| US-20140187712-A1 | FUNCTIONALIZED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2014-07-03 | — | — | US | disclosed |