Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | FABP2 | P12104 | 2/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22209081 | 0.82 | PPARA (0.55) | PPARAPPARGFABP2SLC22A12LMNA | |
| SCHEMBL1584444 | 0.82 | PPARA (0.50) | PPARAPPARGFABP2SLC22A12LMNA | |
| SCHEMBL22221439 | 0.79 | PPARA (0.54) | PPARAPPARGFABP2SLC22A12LMNA | |
| SCHEMBL1584689 | 0.79 | PPARA (0.56) | PPARAPPARGFABP2SLC22A12LMNA | |
| SCHEMBL1583796 | 0.78 | PPARA (0.52) | PPARAPPARGFABP2SLC22A12LMNA | |
| SCHEMBL22221443 | 0.77 | PPARA (0.54) | PPARAPPARGFABP2SLC22A12LMNA | |
| SCHEMBL22221670 | 0.77 | PPARA (0.62) | PPARAPPARGFABP2SLC22A12LMNA | |
| SCHEMBL1584416 | 0.76 | PPARA (0.52) | PPARAPPARGFABP2SLC22A12LMNA | |
| SCHEMBL1584395 | 0.76 | PPARA (0.60) | PPARAPPARGFABP2SLC22A12LMNA | |
| SCHEMBL1583983 | 0.75 | PPARA (0.51) | PPARAPPARGFABP2SLC22A12LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011044141-A1 | FATTY ACID FIBRATE DERIVATIVES AND THEIR USES | CATABASIS PHARMACEUTICALS, INC. (US) | 2011-04-14 | — | — | WO | disclosed |