SCHEMBL1584510

SCHEMBL1584510

O=C(O)CC1CCCN1c1cccc(Oc2ccccc2)c1

nearest known ligand 0.81

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 0.81
PPARG P37231 2/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1605087 0.90 FFAR1 (1.00) FFAR1PPARG
SCHEMBL1605086 0.90 FFAR1 (1.00) FFAR1PPARG
SCHEMBL12708146 0.90 FFAR1 (1.00) FFAR1PPARG
SCHEMBL12721038 0.89 FFAR1 (0.68) FFAR1PPARG
SCHEMBL1584853 0.87 FFAR1 (0.80) FFAR1PPARG
SCHEMBL1584578 0.87 FFAR1 (0.80) FFAR1PPARG
SCHEMBL1584693 0.87 FFAR1 (0.80) FFAR1PPARG
SCHEMBL1584219 0.86 FFAR1 (0.78) FFAR1PPARG
SCHEMBL12708151 0.86 FFAR1 (1.00) FFAR1PPARG
SCHEMBL12708150 0.86 FFAR1 (1.00) FFAR1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2486005-A1 PYRROLIDINE GPR40 MODULATORS Bristol-Myers Squibb Company (US) 2012-08-15 EP disclosed
WO-2011044073-A1 PYRROLIDINE GPR40 MODULATORS BRISTOL-MYERS SQUIBB COMPANY (US) 2011-04-14 WO disclosed