Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1604379 | 0.82 | FFAR1 (0.66) | FFAR1PPARG | |
| SCHEMBL1585314 | 0.82 | FFAR1 (0.66) | FFAR1PPARG | |
| SCHEMBL1584602 | 0.82 | CD274 (0.48) | FFAR1PPARGCD274 | |
| SCHEMBL1584512 | 0.77 | FFAR1 (0.72) | FFAR1PPARG | |
| SCHEMBL1584234 | 0.75 | FFAR1 (0.63) | FFAR1PPARG | |
| SCHEMBL12708083 | 0.74 | FFAR1 (0.55) | FFAR1PPARG | |
| SCHEMBL1604246 | 0.73 | FFAR1 (0.53) | FFAR1PPARGSMN1; SMN2 | |
| SCHEMBL1604245 | 0.73 | FFAR1 (0.53) | FFAR1PPARGSMN1; SMN2 | |
| SCHEMBL1584814 | 0.73 | FFAR1 (0.56) | FFAR1PPARGMEN1ALDH1A1KMT2A | |
| SCHEMBL1584543 | 0.72 | FFAR1 (0.60) | FFAR1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2486005-A1 | PYRROLIDINE GPR40 MODULATORS | Bristol-Myers Squibb Company (US) | 2012-08-15 | — | — | EP | disclosed |
| WO-2011044073-A1 | PYRROLIDINE GPR40 MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-04-14 | — | — | WO | disclosed |