SCHEMBL15847351

SCHEMBL15847351

CCCCCCC[Si](CCCCCCC)(OCCC)OCCC

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.40
THRB P10828 2/20 0.40
DNM1 Q05193 8/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ALDH1A1 P00352 1/20 0.38
EPHX1 P07099 1/20 0.38
HTT P42858 2/20 0.33
USP2 O75604 1/20 0.33
NR5A1 Q13285 1/20 0.33
MAPT P10636 1/20 0.33
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2495549 1.00 TSHR (0.40) TSHRTHRBDNM1MEN1KMT2A
SCHEMBL31286333 1.00 TSHR (0.40) TSHRTHRBDNM1MEN1KMT2A
SCHEMBL31286344 1.00 TSHR (0.40) TSHRTHRBDNM1MEN1KMT2A
SCHEMBL15846783 1.00 TSHR (0.40) TSHRTHRBDNM1MEN1KMT2A
SCHEMBL31286380 1.00 TSHR (0.40) TSHRTHRBDNM1MEN1KMT2A
SCHEMBL15847227 1.00 TSHR (0.40) TSHRTHRBDNM1MEN1KMT2A
SCHEMBL11358144 1.00 TSHR (0.40) TSHRTHRBDNM1MEN1KMT2A
SCHEMBL8978864 0.97 TSHR (0.35) TSHRTHRBDNM1MEN1KMT2A
SCHEMBL5574591 0.95 TSHR (0.36) TSHRTHRBDNM1MEN1KMT2A
SCHEMBL5573896 0.95 TSHR (0.36) TSHRTHRBDNM1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150329727-A1 A COATING COMPOSITION, A PREPARATION METHOD THEREFORE, AND USE THEREOF AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2015-11-19 US claimed
EP-2938753-A1 A COATING COMPOSITION, A PREPARATION METHOD THEREFORE, AND USE THEREOF Akzo Nobel Coatings International B.V. (NL) 2015-11-04 EP claimed
CN-104968834-A A coating composition, a preparation method therefore, and use thereof AKZO NOBEL COATINGS INT BV 2015-10-07 CN claimed
WO-2014102166-A9 A COATING COMPOSITION, A PREPARATION METHOD THEREFORE, AND USE THEREOF AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2014-09-18 WO claimed
WO-2014102166-A1 A COATING COMPOSITION, A PREPARATION METHOD THEREFORE, AND USE THEREOF AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2014-07-03 WO claimed
CN-104968834-B Coating composition, Its Preparation Method And Use 阿克佐诺贝尔国际涂料股份有限公司 2018-05-01 CN disclosed
US-20150329727-A1 A COATING COMPOSITION, A PREPARATION METHOD THEREFORE, AND USE THEREOF AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2015-11-19 US disclosed
EP-2938753-A1 A COATING COMPOSITION, A PREPARATION METHOD THEREFORE, AND USE THEREOF Akzo Nobel Coatings International B.V. (NL) 2015-11-04 EP disclosed
CN-104968834-A A coating composition, a preparation method therefore, and use thereof AKZO NOBEL COATINGS INT BV 2015-10-07 CN disclosed
WO-2014102166-A9 A COATING COMPOSITION, A PREPARATION METHOD THEREFORE, AND USE THEREOF AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2014-09-18 WO disclosed
WO-2014102166-A1 A COATING COMPOSITION, A PREPARATION METHOD THEREFORE, AND USE THEREOF AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2014-07-03 WO disclosed