Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 11/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.50 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15848417 | 1.00 | PRCP (0.68) | PRCPCYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL6128238 | 0.99 | PRCP (0.70) | PRCPCYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL3343952 | 0.93 | PRCP (0.61) | PRCPCYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL15848586 | 0.89 | PRCP (0.56) | PRCPCYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL15848588 | 0.89 | PRCP (0.56) | PRCPCYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL16498829 | 0.89 | PRCP (0.59) | PRCPCYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL15848395 | 0.88 | PRCP (0.57) | PRCPCYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL15848314 | 0.88 | PRCP (0.68) | PRCPCYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL15848315 | 0.88 | PRCP (0.68) | PRCPCYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL3448550 | 0.88 | PRCP (0.55) | PRCPCYP3A4CYP2C9NR1I2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170129916-A1 | NOVEL BETULINIC PROLINE IMIDAZOLE DERIVATIVES AS HIV INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2017-05-11 | — | — | US | disclosed |
| US-9637516-B2 | Betulinic acid proline derivatives as HIV inhibitors | HETERO RESEARCH FOUNDATION (IN) | 2017-05-02 | — | — | US | disclosed |
| US-20150337004-A1 | NOVEL BETULINIC ACID PROLINE DERIVATIVES AS HIV INHIBITORS | HETERO LABS LIMITED (IN) | 2015-11-26 | — | — | US | disclosed |
| WO-2014105926-A1 | NOVEL BETULINIC ACID PROLINE DERIVATIVES AS HIV INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2014-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170129916-A1 | NOVEL BETULINIC PROLINE IMIDAZOLE DERIVATIVES AS HIV INHIBITORS | BET1, PRR12, PREP | PRCP 501/4885CYP3A4 3355/4885CYP2C9 4010/4885 |
| US-20150337004-A1 | NOVEL BETULINIC ACID PROLINE DERIVATIVES AS HIV INHIBITORS | BET1, PRR12, PELP1 | PRCP 372/4885CYP3A4 3717/4885CYP2C9 4027/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.