SCHEMBL15848628

SCHEMBL15848628

Cc1nn(C2CCCCO2)c2sc(C(=O)Nc3cccc(S(=O)(=O)CCO[Si](C)(C)C(C)(C)C)c3)cc12

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PDE7A Q13946 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL852940 0.89 PDE7A (0.59) PDE7A
SCHEMBL853934 0.76 PDE7A (0.65) PDE7A
SCHEMBL880748 0.75 PDE7A (0.59) PDE7A
SCHEMBL853242 0.72 PDE7A (1.00) PDE7A
SCHEMBL854466 0.72 PDE7A (0.70) PDE7A
SCHEMBL854045 0.70 PDE7A (0.67) PDE7A
SCHEMBL854185 0.69 PDE7A (1.00) PDE7A
SCHEMBL854341 0.69 PDE7A (1.00) PDE7A
Hydrochloric Acid SCHEMBL853843 0.69 PDE7A (0.98) PDE7A
SCHEMBL854249 0.68 PDE7A (0.81) PDE7A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014102497-A1 DERMATOLOGICAL COMPOSITION COMPRISING A PDE7 INHIBITOR IN A SOLUBILISED FORM, PRODUCTION METHOD THEREOF, AND USE OF SAME GALDERMA RESEARCH & DEVELOPMENT (FR) 2014-07-03 WO disclosed