SCHEMBL15848788

SCHEMBL15848788

Brc1ccc2c(c1)[nH]c1ccc3cc4ccccc4cc3c12

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 9/20 0.46
CCND1 P24385 9/20 0.46
CYP2A6 P11509 1/20 0.44
CCNE2 O96020 3/20 0.43
CCNE1 P24864 3/20 0.43
CDK2 P24941 3/20 0.43
CCNB2 O95067 2/20 0.43
CDK1 P06493 2/20 0.43
CCNB1 P14635 2/20 0.43
CCNB3 Q8WWL7 2/20 0.43
CAMK2B Q13554 2/20 0.43
CAMK2G Q13555 2/20 0.43
CAMK2D Q13557 2/20 0.43
CAMK2A Q9UQM7 2/20 0.43
CCNT1 O60563 1/20 0.43
EIF2AK2 P19525 1/20 0.43
CCNA2 P20248 1/20 0.43
CDK9 P50750 1/20 0.43
CDK5 Q00535 1/20 0.43
CDK5R1 Q15078 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31622 0.87 CDK4 (0.51) CDK4CCND1CYP2A6CCNE2CCNE1
SCHEMBL30221171 0.87 CDK4 (0.51) CDK4CCND1CYP2A6CCNE2CCNE1
SCHEMBL30849130 0.87 CDK4 (0.51) CDK4CCND1CYP2A6CCNE2CCNE1
SCHEMBL12219466 0.83 CDK4 (0.49) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL17023948 0.82 CDK4 (0.54) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL17023957 0.82 CDK4 (0.54) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL12776872 0.82 CDK4 (0.65) CDK4CCND1GABRPGABRDGABRA1
SCHEMBL31484361 0.82 CDK4 (0.65) CDK4CCND1GABRPGABRDGABRA1
SCHEMBL12219445 0.81 CDK4 (0.51) CDK4CCND1CCNE2CCNE1CDK2
SCHEMBL12219439 0.81 CYP1A2 (0.47) CDK4CCND1GABRPGABRDGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8766243-B2 Heterocycle-containing asymmetric aromatic compound, compound for organic thin film transistor, and organic thin film transistor using the same IDEMITSU KOSAN CO., LTD. (JP) 2014-07-01 US disclosed