Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL369149 | 0.80 | GPBAR1 (0.42) | BRD4GPBAR1MEN1KMT2AHTT | |
| SCHEMBL369151 | 0.80 | GPBAR1 (0.42) | BRD4GPBAR1MEN1KMT2AHTT | |
| SCHEMBL369150 | 0.80 | GPBAR1 (0.42) | BRD4GPBAR1MEN1KMT2AHTT | |
| SCHEMBL368377 | 0.76 | GPBAR1 (0.53) | BRD4GPBAR1MEN1KMT2AHTT | |
| SCHEMBL369354 | 0.76 | FFAR1 (0.33) | BRD4GPBAR1MEN1KMT2AHTT | |
| SCHEMBL369353 | 0.76 | FFAR1 (0.33) | BRD4GPBAR1MEN1KMT2AHTT | |
| SCHEMBL368376 | 0.76 | GPBAR1 (0.53) | BRD4GPBAR1MEN1KMT2AHTT | |
| SCHEMBL1389678 | 0.75 | GPBAR1 (0.51) | BRD4GPBAR1MEN1KMT2AHTT | |
| SCHEMBL1389680 | 0.75 | GPBAR1 (0.51) | BRD4GPBAR1MEN1KMT2AHTT | |
| SCHEMBL369998 | 0.74 | GPBAR1 (0.45) | BRD4GPBAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8765730-B2 | 1-hydroxyimino-3-phenyl-propanes | Hoffmann-La Roche Inc (US) | 2014-07-01 | — | — | US | disclosed |