Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 18/20 | 0.48 |
| ▸ | EGLN2 | Q96KS0 | 8/20 | 0.45 |
| ▸ | EGLN3 | Q9H6Z9 | 8/20 | 0.45 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.45 |
| ▸ | OGFOD1 | Q8N543 | 1/20 | 0.41 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.41 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.38 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585655 | 0.85 | EGLN1 (0.50) | EGLN1EGLN2EGLN3OGFOD1HIF1AN | |
| SCHEMBL1586198 | 0.84 | HIF1A (0.49) | EGLN1EGLN2EGLN3OGFOD1HIF1AN | |
| SCHEMBL1585860 | 0.83 | HIF1A (0.49) | EGLN1EGLN2EGLN3OGFOD1HIF1AN | |
| SCHEMBL1586428 | 0.83 | EGLN1 (0.49) | EGLN1EGLN2EGLN3CYSLTR2HIF1A | |
| SCHEMBL3730753 | 0.78 | EGLN1 (0.53) | EGLN1EGLN2EGLN3CYSLTR2HIF1A | |
| SCHEMBL1585640 | 0.77 | EGLN1 (0.46) | EGLN1EGLN2EGLN3OGFOD1HIF1AN | |
| SCHEMBL1586298 | 0.77 | HIF1A (0.45) | EGLN1EGLN2EGLN3OGFOD1HIF1AN | |
| SCHEMBL1586253 | 0.77 | EGLN1 (0.46) | EGLN1EGLN2EGLN3OGFOD1HIF1AN | |
| SCHEMBL1586493 | 0.74 | EGLN1 (0.47) | EGLN1EGLN2EGLN3HIF1A | |
| SCHEMBL1585691 | 0.71 | OGFRL1 (0.49) | EGLN1EGLN2EGLN3OGFOD1HIF1AN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048611-A1 | NOVEL FUSED PYRIDAZINE DERIVATIVES | TORRENT PHARMACEUTICALS LIMITED (IN) | 2011-04-28 | — | — | WO | disclosed |