Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 19/20 | 0.63 |
| ▸ | FER | P16591 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14929283 | 1.00 | SYK (0.63) | SYKFER | |
| SCHEMBL14908661 | 1.00 | SYK (0.63) | SYKFER | |
| SCHEMBL14908662 | 1.00 | SYK (0.63) | SYKFER | |
| SCHEMBL14923766 | 0.94 | SYK (0.61) | SYKFER | |
| SCHEMBL14929382 | 0.94 | SYK (0.61) | SYKFER | |
| SCHEMBL14910381 | 0.94 | SYK (0.61) | SYKFER | |
| SCHEMBL14910382 | 0.94 | SYK (0.61) | SYKFER | |
| SCHEMBL15855941 | 0.94 | SYK (0.61) | SYKFER | |
| SCHEMBL14909034 | 0.91 | SYK (0.60) | SYK | |
| SCHEMBL14911339 | 0.91 | SYK (0.60) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2589592-B1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | FUJIFILM CORP (JP) | 2018-08-22 | — | — | EP | claimed |
| US-8895585-B2 | Nicotinamide derivative or salt thereof | FUJIFILM CORPORATION (JP) | 2014-11-25 | — | — | US | claimed |
| US-8809371-B2 | — | — | 2014-08-19 | — | — | US | claimed |
| US-8772320-B2 | — | — | 2014-07-08 | — | — | US | claimed |
| EP-2589592-B1 | NOVEL NICOTINAMIDE DERIVATIVES OR SALTS THEREOF | FUJIFILM CORP (JP) | 2018-08-22 | — | — | EP | disclosed |