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SCHEMBL15857448

SCHEMBL15857448

c1ccc(-c2nc(-c3ccccc3)nc(-c3cccc(-c4ccc(-n5c6cc7c8ccccc8n(-c8ccccc8)c7cc6c6ccc7c(ccn7-c7ccccc7)c65)cc4)c3)n2)cc1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.35
▸ ATM Q13315 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ PTGER4 P35408 1/20 0.32
▸ NR3C1 P04150 1/20 0.31
▸ HTR7 P34969 1/20 0.30
▸ HDAC4 P56524 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15857400 0.97 KDM4E (0.35) KDM4EATML3MBTL1PTGER4NR3C1
SCHEMBL20427183 0.96 KDM4E (0.35) KDM4EATML3MBTL1PTGER4NR3C1
SCHEMBL15857372 0.95 KDM4E (0.36) KDM4EATML3MBTL1PTGER4
SCHEMBL15857447 0.95 KDM4E (0.39) KDM4EATML3MBTL1PTGER4HTR7
SCHEMBL15857403 0.94 KDM4E (0.34) KDM4EATML3MBTL1PTGER4NR3C1
SCHEMBL15802239 0.94 KDM4E (0.35) KDM4EATML3MBTL1PTGER4NR3C1
SCHEMBL15801693 0.94 KDM4E (0.35) KDM4EATML3MBTL1PTGER4NR3C1
SCHEMBL15857446 0.93 KDM4E (0.38) KDM4EATML3MBTL1PTGER4
SCHEMBL15748862 0.93 KDM4E (0.39) KDM4EATML3MBTL1PTGER4NR3C1
SCHEMBL15748676 0.93 KDM4E (0.39) KDM4EATML3MBTL1PTGER4NR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014104663-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME 주식회사 두산 (KR) 2014-07-03 — — WO disclosed
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