SCHEMBL15859151

SCHEMBL15859151

N#CC(=Cc1ccc(-c2ccccc2)s1)C(=O)O

nearest known ligand 0.74

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.74
APP P05067 1/20 0.60
KMT2A Q03164 5/20 0.51
ALDH1A1 P00352 3/20 0.51
HPGD P15428 2/20 0.51
TDP1 Q9NUW8 1/20 0.51
KDM4E B2RXH2 4/20 0.47
MEN1 O00255 2/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
LMNA P02545 3/20 0.44
PKM P14618 1/20 0.44
PSMD14 O00487 1/20 0.44
CISD1 Q9NZ45 1/20 0.44
SLC16A3 O15427 1/20 0.44
CYP3A4 P08684 1/20 0.44
SLC16A1 P53985 1/20 0.44
GPR35 Q9HC97 1/20 0.44
EGFR P00533 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14730414 1.00 MAPT (0.74) MAPTAPPKMT2AALDH1A1HPGD
SCHEMBL15859149 1.00 MAPT (0.74) MAPTAPPKMT2AALDH1A1HPGD
SCHEMBL11937001 0.90 MAPT (0.89) MAPTAPPKMT2AALDH1A1HPGD
SCHEMBL12327644 0.88 MAPT (0.95) MAPTAPPKMT2AALDH1A1HPGD
SCHEMBL13931301 0.88 MAPT (0.95) MAPTAPPKMT2AALDH1A1HPGD
SCHEMBL18318019 0.88 MAPT (0.95) MAPTAPPKMT2AALDH1A1HPGD
SCHEMBL12327831 0.88 MAPT (0.95) MAPTAPPKMT2AALDH1A1HPGD
SCHEMBL7006827 0.87 MAPT (0.93) MAPTAPPKMT2AALDH1A1HPGD
SCHEMBL12294107 0.86 MAPT (1.00) MAPTAPPKMT2AALDH1A1HPGD
SCHEMBL12327641 0.86 MAPT (1.00) MAPTAPPKMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017102014-A1 PROPENAMIDE THIOPHENE DERIVATIVES AS FLAVIVIRUS INHIBITORS AND THEIR USE UNIVERSITE D'AIX-MARSEILLE (FR) 2017-06-22 WO disclosed
US-20140202537-A1 DYE-SENSITIZED SOLAR CELL AND SENSITIZING DYE NATIONAL INSTITUTE FOR MATERIALS SCIENCE (JP) 2014-07-24 US disclosed
EP-2752935-A1 DYE-SENSITIZED SOLAR CELL AND SENSITIZING DYE National Institute for Materials Science (JP) 2014-07-09 EP disclosed