Mebendazole

Mebendazole

SCHEMBL15860

COC(=O)Nc1nc2cc(C(=O)c3ccccc3)ccc2[nH]1

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 4/20 0.82
LMNA P02545 3/20 0.82
CYP1A2 P05177 3/20 0.82
ALDH1A1 P00352 3/20 0.82
KDR P35968 2/20 0.82
CYP2C9 P11712 2/20 0.82
HTT P42858 2/20 0.82
HIF1A Q16665 2/20 0.82
ABCC4 O15439 1/20 0.82
USP2 O75604 1/20 0.82
MAPK1 P28482 2/20 0.65
ADORA3 P0DMS8 1/20 0.65
PTGS1 P23219 1/20 0.65
RXFP1 Q9HBX9 1/20 0.65
RAF1 P04049 6/20 0.62
BRAF P15056 6/20 0.62
SCD O00767 1/20 0.60
TUBB4A P04350 3/20 0.57
TUBB P07437 3/20 0.57
TUBA3C P0DPH7 3/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mebendazole SCHEMBL29409261 1.00 ABL1 (0.82) ABL1LMNACYP1A2ALDH1A1KDR
Mebendazole SCHEMBL3429179 1.00 ABL1 (0.82) ABL1LMNACYP1A2ALDH1A1KDR
Mebendazole SCHEMBL21051203 0.99 ABL1 (0.80) ABL1LMNACYP1A2ALDH1A1KDR
Mebendazole SCHEMBL17262440 0.99 ABL1 (0.80) ABL1LMNACYP1A2ALDH1A1KDR
Mebendazole SCHEMBL21051200 0.99 ABL1 (0.80) ABL1LMNACYP1A2ALDH1A1KDR
Mebendazole SCHEMBL27690766 0.99 ABL1 (0.80) ABL1LMNACYP1A2ALDH1A1KDR
Mebendazole SCHEMBL28186589 0.99 ABL1 (0.80) ABL1LMNACYP1A2ALDH1A1KDR
Mebendazole SCHEMBL28588780 0.98 ABL1 (0.78) ABL1LMNACYP1A2ALDH1A1KDR
Mebendazole SCHEMBL21051204 0.95 ABL1 (0.75) ABL1LMNACYP1A2ALDH1A1KDR
Mebendazole SCHEMBL28858902 0.95 ABL1 (0.75) ABL1LMNACYP1A2ALDH1A1KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 15556 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724049-A1 MODIFIED RELEASE FILL COMPOSITIONS FOR DOSAGE FORMS AND METHODS OF PREPARATION AND USE THEREOF Catalent Ontario Limited (CA) 2026-04-15 EP claimed
WO-2026044269-A1 COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING ALZHEIMER'S DISEASE AND OTHER SAFWAT SHERIF (US) 2026-02-26 WO claimed
EP-4680203-A1 COMPOSITIONS FOR SUSTAINED RELEASE OF POORLY SOLUBLE ACTIVE INGREDIENTS Prolevi Bio AB (SE) 2026-01-21 EP claimed
US-12496374-B2 Deodorizer composition, absorbing body, and absorbent article SUMITOMO SEIKA CHEMICALS CO, LTD. (JP) 2025-12-16 US claimed
US-20250375422-A1 METHOD FOR TREATING CANCERS ACURA NANOMEDICINE CORP (TW) 2025-12-11 US claimed
US-20250352518-A1 A BENZIMIDAZOLE COMPOUND WITH ANTIHELMINTHIC ACTIVITY FOR USE IN REVERSING, ARRESTING OR SLOWING DOWN CELLULAR AGEING IN A VERTEBRATE SUBJECT RAVAN BIO LIMITED (GB) 2025-11-20 US claimed
US-12465623-B2 Use of parasites and extracellular vesicles obtained from parasites in cancer treatment YEDITEPE UNIVERSITESI (TR) 2025-11-11 US claimed
US-20250339399-A1 SUPRAMOLECULAR SELF-ASSEMBLY SYSTEM BEIJING CREATRON INSTITUTE OF PHARMACEUTICAL RES CO LTD (CN) 2025-11-06 US claimed
EP-4633617-A1 USE OF BORON FOR THE TREATMENT OF LEISHMANIASIS DISEASE Yeditepe Universitesi (TR) 2025-10-22 EP claimed
EP-4633643-A1 USE OF BORON FOR THE TREATMENT OF LEISHMANIASIS DISEASE OF NEURONAL ORIGIN Yeditepe Universitesi (TR) 2025-10-22 EP claimed
US-4704118-A Ruminant dispensing device with thermo-activated memory ALZA CORPORATION (US) 1987-11-03 US claimed
EP-0090368-B1 ANTHELMINTIC PREPARATIONS HOECHST UK LIMITED (GB) 1987-09-02 EP claimed
US-4675174-A Veterinary dispenser delivering beneficial agent by gas power generated in situ ALZA CORPORATION (US) 1987-06-23 US claimed
EP-0224249-A1 Amorphous benzimidazole derivatives SYNTEX (U.S.A.) INC. (US) 1987-06-03 EP claimed
US-4643893-A FOR ADMINISTERING MEDICINE TO ANIMAL RUMEN C.R.B. VIRBAC S.A. (FR) 1987-02-17 US claimed
EP-0202568-A1 Anthelmintic compositions SYNTEX (U.S.A.) INC. (US) 1986-11-26 EP claimed
EP-0100448-B1 LIQUID, ACTIVE AGENT FORMULATIONS AND THEIR USE IN PREPARING MICRO-EMULSIONS A. Nattermann & Cie. GmbH (DE) 1986-08-27 EP claimed
US-4595583-A Delivery system controlled administration of beneficial agent to ruminants ALZA CORPORATION (US) 1986-06-17 US claimed
EP-0090368-A1 Anthelmintic preparations HOECHST UK LIMITED (GB) 1983-10-05 EP claimed
US-4009266-A METHOD OF TREATMENT OF NEMATODE PARASITE INFECTIONS IN DOMESTIC ANIMALS AYALEW LIYEW 1977-02-22 US claimed