Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 7/20 | 0.46 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.43 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 9/20 | 0.41 |
| ▸ | EGLN3 | Q9H6Z9 | 3/20 | 0.40 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1585620 | 0.86 | EGLN1 (0.48) | EGLN1EGLN2HIF1AEGLN3 | |
| SCHEMBL1586324 | 0.85 | EGLN1 (0.45) | EGLN1FTOEGLN2HIF1A | |
| SCHEMBL1586094 | 0.85 | EGLN1 (0.44) | EGLN1EGLN3 | |
| SCHEMBL1585884 | 0.84 | EGLN1 (0.43) | EGLN1EGLN2HIF1AEGLN3 | |
| SCHEMBL1586566 | 0.80 | EGLN1 (0.46) | EGLN1HIF1A | |
| SCHEMBL1585967 | 0.79 | EGLN1 (0.45) | EGLN1HIF1A | |
| SCHEMBL1586070 | 0.79 | HIF1A (0.49) | EGLN1EGLN2HIF1AEGLN3 | |
| SCHEMBL1586442 | 0.78 | HIF1A (0.48) | EGLN1EGLN2HIF1AEGLN3 | |
| SCHEMBL1585831 | 0.78 | HIF1A (0.48) | EGLN1HIF1AEGLN3 | |
| SCHEMBL2576889 | 0.77 | EGLN1 (0.59) | EGLN1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011048611-A1 | NOVEL FUSED PYRIDAZINE DERIVATIVES | TORRENT PHARMACEUTICALS LIMITED (IN) | 2011-04-28 | — | — | WO | claimed |