SCHEMBL15864686

SCHEMBL15864686

C=C(C)C(=O)OCC(Oc1ccccc1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.45
SLC6A4 P31645 3/20 0.44
MTNR1A P48039 1/20 0.40
MTNR1B P49286 1/20 0.40
ELANE P08246 1/20 0.40
POLB P06746 1/20 0.39
APEX1 P27695 1/20 0.39
HTT P42858 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
CHRM1 P11229 1/20 0.39
SLC6A9 P48067 6/20 0.38
HPGD P15428 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
PABPC1 P11940 1/20 0.37
APOBEC3A P31941 1/20 0.37
APOBEC3G Q9HC16 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL57281 0.85 TSHR (0.47) TSHRMTNR1AMTNR1BELANEPOLB
SCHEMBL301505 0.82 TSHR (0.56) TSHRMTNR1AMTNR1BELANEPOLB
SCHEMBL17938235 0.82 TSHR (0.47) TSHRMTNR1AMTNR1BELANEPOLB
Ethylene Glycol SCHEMBL21772119 0.81 TSHR (0.44) TSHRELANEPOLBAPEX1HTT
SCHEMBL5958652 0.81 TSHR (0.44) TSHRELANEPOLBAPEX1HTT
SCHEMBL3180135 0.81 TSHR (0.53) TSHRMTNR1AMTNR1BELANEPOLB
SCHEMBL10792065 0.81 TSHR (0.46) TSHRMTNR1AMTNR1BELANEPOLB
SCHEMBL10794410 0.81 TSHR (0.46) TSHRMTNR1AMTNR1BELANEPOLB
SCHEMBL3684751 0.80 TSHR (0.42) TSHRELANEPOLBAPEX1HTT
SCHEMBL10600347 0.79 TSHR (0.45) TSHRMTNR1AMTNR1BELANEPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2941445-B1 FLEXIBLE, HIGH REFRACTIVE INDEX HYDROPHOBIC COPOLYMER COUNCIL SCIENT IND RES (IN) 2017-03-22 EP claimed
US-20150353667-A1 FLEXIBLE, HIGH REFRACTIVE INDEX HYDROPHOBIC COPOLYMER COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-12-10 US claimed
EP-2941445-A1 FLEXIBLE, HIGH REFRACTIVE INDEX HYDROPHOBIC COPOLYMER Council of Scientific & Industrial Research (IN) 2015-11-11 EP claimed
WO-2014106866-A1 FLEXIBLE, HIGH REFRACTIVE INDEX HYDROPHOBIC COPOLYMER COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2014-07-10 WO claimed
EP-2941445-B1 FLEXIBLE, HIGH REFRACTIVE INDEX HYDROPHOBIC COPOLYMER COUNCIL SCIENT IND RES (IN) 2017-03-22 EP disclosed
EP-2941445-B1 FLEXIBLE, HIGH REFRACTIVE INDEX HYDROPHOBIC COPOLYMER COUNCIL SCIENT IND RES (IN) 2017-03-22 EP disclosed
US-9505700-B2 High refractive index (meth) acrylates COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2016-11-29 US disclosed
US-9505700-B2 High refractive index (meth) acrylates COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2016-11-29 US disclosed
EP-2864285-B1 HIGH REFRACTIVE INDEX (METH)ACRYLATES COUNCIL SCIENT IND RES (IN) 2016-10-19 EP disclosed
US-20150353667-A1 FLEXIBLE, HIGH REFRACTIVE INDEX HYDROPHOBIC COPOLYMER COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-12-10 US disclosed
US-20150353667-A1 FLEXIBLE, HIGH REFRACTIVE INDEX HYDROPHOBIC COPOLYMER COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-12-10 US disclosed
EP-2941445-A1 FLEXIBLE, HIGH REFRACTIVE INDEX HYDROPHOBIC COPOLYMER Council of Scientific & Industrial Research (IN) 2015-11-11 EP disclosed
WO-2014106866-A1 FLEXIBLE, HIGH REFRACTIVE INDEX HYDROPHOBIC COPOLYMER COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2014-07-10 WO disclosed