Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1586791 | 1.00 | HCRTR1 (0.57) | HCRTR1HCRTR2 | |
| SCHEMBL1586097 | 0.90 | HCRTR1 (0.69) | HCRTR1HCRTR2 | |
| SCHEMBL6908861 | 0.88 | HCRTR1 (0.68) | HCRTR1HCRTR2 | |
| SCHEMBL1586175 | 0.86 | HCRTR1 (0.58) | HCRTR1HCRTR2 | |
| SCHEMBL1586742 | 0.85 | HCRTR1 (0.70) | HCRTR1HCRTR2 | |
| SCHEMBL1586339 | 0.85 | HCRTR1 (0.70) | HCRTR1HCRTR2 | |
| SCHEMBL1586124 | 0.79 | HCRTR1 (0.67) | HCRTR1HCRTR2 | |
| SCHEMBL6907744 | 0.77 | HCRTR1 (0.52) | HCRTR1HCRTR2 | |
| SCHEMBL1586847 | 0.75 | HCRTR1 (0.56) | HCRTR1HCRTR2 | |
| SCHEMBL1586290 | 0.75 | HCRTR1 (0.56) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2491031-A1 | FUSED HETEROCYCLIC COMPOUNDS AS OREXIN RECEPTOR MODULATORS | Janssen Pharmaceutica N.V. (BE) | 2012-08-29 | — | — | EP | disclosed |
| WO-2011050202-A1 | FUSED HETEROCYCLIC COMPOUNDS AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-04-28 | — | — | WO | disclosed |