⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15869239 | 0.86 | — | — | |
| SCHEMBL15869253 | 0.86 | — | — | |
| SCHEMBL15869240 | 0.80 | — | — | |
| SCHEMBL15869232 | 0.77 | — | — | |
| SCHEMBL15869241 | 0.77 | — | — | |
| SCHEMBL15869235 | 0.71 | — | — | |
| SCHEMBL15869236 | 0.71 | — | — | |
| SCHEMBL15869251 | 0.71 | — | — | |
| SCHEMBL15869231 | 0.68 | — | — | |
| SCHEMBL15869238 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9642836-B2 | Isotopologues of isoindole derivatives | CELGENE CORPORATION (US) | 2017-05-09 | — | — | US | disclosed |
| US-20150258063-A1 | ISOTOPOLOGUES OF ISOINDOLE DERIVATIVES | AMGEN INC. | 2015-09-17 | — | — | US | disclosed |
| US-9045417-B2 | Isotopologues of isoindole derivatives | CELGENE CORPORATION (US) | 2015-06-02 | — | — | US | disclosed |
| US-20140194485-A1 | ISOTOPOLOGUES OF ISOINDOLE DERIVATIVES | CELGENE CORPORATION (US) | 2014-07-10 | — | — | US | disclosed |