Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.97 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.97 |
| ▸ | C9 | P02748 | 3/20 | 0.97 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.97 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.97 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.97 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.97 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.97 |
| ▸ | APEX1 | P27695 | 2/20 | 0.97 |
| ▸ | CTH | P32929 | 2/20 | 0.97 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.97 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.97 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.97 |
| ▸ | THRB | P10828 | 2/20 | 0.97 |
| ▸ | HPGD | P15428 | 2/20 | 0.97 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.97 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.97 |
| ▸ | RECQL | P46063 | 2/20 | 0.97 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.97 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.97 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aurintricarboxylic Acid SCHEMBL29353681 | 0.99 | MEN1 (1.00) | MEN1KMT2AC9CYP2C9CYP2C19 | |
| Aurintricarboxylic Acid SCHEMBL98495 | 0.99 | MEN1 (1.00) | MEN1KMT2AC9CYP2C9CYP2C19 | |
| Aurintricarboxylic Acid SCHEMBL29450069 | 0.99 | MEN1 (1.00) | MEN1KMT2AC9CYP2C9CYP2C19 | |
| Aurintricarboxylic Acid SCHEMBL30831678 | 0.97 | MEN1 (0.97) | MEN1KMT2AC9CYP2C9CYP2C19 | |
| Aurintricarboxylic Acid SCHEMBL6158321 | 0.97 | MEN1 (0.97) | MEN1KMT2AC9CYP2C9CYP2C19 | |
| Aurintricarboxylic Acid SCHEMBL29395768 | 0.97 | MEN1 (0.97) | MEN1KMT2AC9CYP2C9CYP2C19 | |
| Aurintricarboxylic Acid SCHEMBL10791075 | 0.97 | MEN1 (0.97) | MEN1KMT2AC9CYP2C9CYP2C19 | |
| Aurintricarboxylic Acid SCHEMBL4644958 | 0.97 | MEN1 (0.97) | MEN1KMT2AC9CYP2C9CYP2C19 | |
| Aurintricarboxylic Acid SCHEMBL515038 | 0.97 | MEN1 (0.97) | MEN1KMT2AC9CYP2C9CYP2C19 | |
| Aurintricarboxylic Acid SCHEMBL6847597 | 0.96 | MEN1 (0.95) | MEN1KMT2AC9CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340883-A1 | USE OF iNOS INHIBITORS TO INCREASE VIRAL YIELD IN CULTURE | GENZYME CORPORATION | 2022-10-27 | — | — | US | disclosed |
| US-11299715-B2 | Use of iNOS inhibitors to increase viral yield in culture | GENZYME CORPORATION (GB) | 2022-04-12 | — | — | US | disclosed |
| CN-105008523-B | Use of iNOS inhibitors for increasing virus yield in culture | 建新公司 | 2020-03-27 | — | — | CN | disclosed |
| EP-3521420-A1 | USE OF INOS INHIBITORS TO INCREASE VIRAL YIELD IN CULTURE | Genzyme Corporation (US) | 2019-08-07 | — | — | EP | disclosed |
| EP-3266866-A1 | USE OF INOS INHIBITORS TO INCREASE VIRAL YIELD IN CULTURE | Genzyme Corporation (US) | 2018-01-10 | — | — | EP | disclosed |
| EP-2943567-B1 | USE OF INOS INHIBITORS TO INCREASE VIRAL YIELD IN CULTURE | GENZYME CORP (US) | 2017-09-13 | — | — | EP | disclosed |
| US-20150353899-A1 | USE OF INOS INHIBITORS TO INCREASE VIRAL YIELD IN CULTURE | GENZYME CORPORATION (US) | 2015-12-10 | — | — | US | disclosed |
| EP-2943567-A1 | USE OF INOS INHIBITORS TO INCREASE VIRAL YIELD IN CULTURE | Genzyme Corporation (US) | 2015-11-18 | — | — | EP | disclosed |
| WO-2014110053-A1 | USE OF INOS INHIBITORS TO INCREASE VIRAL YIELD IN CULTURE | GENZYME CORPORATION (US) | 2014-07-17 | — | — | WO | disclosed |