Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15875181 | 0.94 | BTK (0.61) | BTK | |
| SCHEMBL15875348 | 0.89 | BTK (0.70) | BTK | |
| SCHEMBL15875332 | 0.88 | BTK (0.62) | BTK | |
| SCHEMBL15886599 | 0.82 | BTK (0.65) | BTK | |
| SCHEMBL15875765 | 0.81 | BTK (0.61) | BTK | |
| SCHEMBL15875217 | 0.81 | BTK (0.68) | BTK | |
| SCHEMBL15875104 | 0.81 | BTK (0.70) | BTK | |
| SCHEMBL15875103 | 0.80 | BTK (0.68) | BTK | |
| SCHEMBL15875267 | 0.80 | BTK (0.69) | BTK | |
| SCHEMBL174854 | 0.79 | BTK (0.74) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014108820-A1 | SUBSTITUTED 2-PYRAZINONE DERIVATIVES AS KINASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2014-07-17 | — | — | WO | claimed |
| WO-2014108820-A1 | SUBSTITUTED 2-PYRAZINONE DERIVATIVES AS KINASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2014-07-17 | — | — | WO | disclosed |
| WO-2014108820-A1 | SUBSTITUTED 2-PYRAZINONE DERIVATIVES AS KINASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2014-07-17 | — | — | WO | disclosed |