Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15875139 | 0.94 | BTK (0.66) | BTK | |
| SCHEMBL15875104 | 0.93 | BTK (0.70) | BTK | |
| SCHEMBL15875199 | 0.93 | BTK (0.64) | BTK | |
| SCHEMBL15875231 | 0.92 | BTK (0.68) | BTK | |
| SCHEMBL15875182 | 0.92 | BTK (0.65) | BTK | |
| SCHEMBL15875101 | 0.91 | BTK (0.75) | BTK | |
| SCHEMBL15875103 | 0.91 | BTK (0.68) | BTK | |
| SCHEMBL15875213 | 0.90 | BTK (0.64) | BTK | |
| SCHEMBL15875136 | 0.90 | BTK (0.62) | BTK | |
| SCHEMBL15875267 | 0.90 | BTK (0.69) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014108820-A1 | SUBSTITUTED 2-PYRAZINONE DERIVATIVES AS KINASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2014-07-17 | — | — | WO | disclosed |
| WO-2014108820-A1 | SUBSTITUTED 2-PYRAZINONE DERIVATIVES AS KINASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2014-07-17 | — | — | WO | disclosed |