Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 10/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 10/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 10/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 10/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3322190 | 0.82 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3326676 | 0.81 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3327174 | 0.65 | PDE4A (0.61) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3324208 | 0.64 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3324336 | 0.58 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3321333 | 0.58 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3326728 | 0.58 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3326716 | 0.58 | PDE4A (0.65) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3326067 | 0.57 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3322736 | 0.57 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2032585-B1 | SUBSTITUTED PTERIDINES AS THERAPEUTIC AGENTS | BOEHRINGER INGELHEIM INT (DE) | 2014-07-23 | — | — | EP | disclosed |