Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | GHSR | Q92847 | 9/20 | 0.42 |
| ▸ | MC4R | P32245 | 2/20 | 0.40 |
| ▸ | MC5R | P33032 | 1/20 | 0.40 |
| ▸ | MC3R | P41968 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 6/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 5/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.38 |
| ▸ | IL1RN | P18510 | 3/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| D-Tryptophan SCHEMBL14691271 | 0.97 | KDM4E (0.46) | KDM4EMAPTMEN1LMNAMPO | |
| D-Tryptophan SCHEMBL14691080 | 0.96 | KDM4E (0.46) | KDM4EMAPTMEN1LMNAMPO | |
| D-Tryptophan SCHEMBL14690990 | 0.96 | KDM4E (0.47) | KDM4EMAPTMEN1LMNAMPO | |
| D-Tryptophan SCHEMBL15879548 | 0.93 | KDM4E (0.49) | KDM4EMAPTMEN1LMNAMPO | |
| D-Tryptophan SCHEMBL14691081 | 0.93 | KDM4E (0.49) | KDM4EMAPTMEN1LMNAMPO | |
| D-Tryptophan SCHEMBL14690992 | 0.93 | KDM4E (0.51) | KDM4EMAPTMEN1LMNAMPO | |
| D-Tryptophan SCHEMBL14691273 | 0.93 | KDM4E (0.51) | KDM4EMAPTMEN1LMNAMPO | |
| D-Tryptophan SCHEMBL14691183 | 0.93 | KDM4E (0.51) | KDM4EMAPTMEN1LMNAMPO | |
| Histidine SCHEMBL14690834 | 0.92 | KMT2A (0.52) | KDM4EMAPTMEN1LMNAMPO | |
| D-Tryptophan SCHEMBL14691096 | 0.90 | KDM4E (0.53) | KDM4EMAPTMEN1LMNAMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170088585-A1 | CYCLIC PEPTIDES AND USES THEREOF | BAR-ILAN UNIVERSITY (IL) | 2017-03-30 | — | — | US | disclosed |
| US-9504759-B2 | Surface modified proteinaceous spherical particles and uses thereof | BAR-ILAN UNIVERSITY (IL) | 2016-11-29 | — | — | US | disclosed |
| US-20140205668-A1 | SURFACE MODIFIED PROTEINACEOUS SPHERICAL PARTICLES AND USES THEREOF | BAR-ILAN UNIVERSITY (IL) | 2014-07-24 | — | — | US | disclosed |