SCHEMBL1587972

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5327824	0.90	MAPK1 (0.51)	HPGDMAPK1KDM4EALDH1A1NPC1
	SCHEMBL1587865	0.87	HPGD (0.50)	HPGDMAPK1KDM4EALDH1A1NPC1
	SCHEMBL2001834	0.87	NPSR1 (0.50)	HPGDMAPK1KDM4EALDH1A1NPC1
	SCHEMBL12124264	0.83	POLB (0.61)	HPGDMAPK1KDM4EALDH1A1NPC1
	SCHEMBL16011515	0.83	HDAC1 (0.61)	HPGDMAPK1KDM4EALDH1A1RAB9A
	SCHEMBL2201378	0.81	HDAC1 (0.68)	HPGDMAPK1KDM4EALDH1A1NPC1
	SCHEMBL12313386	0.81	HPGD (0.56)	HPGDMAPK1KDM4EALDH1A1NPC1
	SCHEMBL6455155	0.80	HDAC3 (0.65)	ALDH1A1NPC1RAB9ASMN1; SMN2GAA
	SCHEMBL8593304	0.80	SMN1; SMN2 (0.46)	HPGDALDH1A1NPC1RAB9ASMN1; SMN2
	SCHEMBL70027	0.80	NPSR1 (0.67)	HPGDMAPK1KDM4EALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.