⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25187984 | 0.73 | — | — | |
| SCHEMBL6864335 | 0.62 | — | — | |
| SCHEMBL11954073 | 0.62 | — | — | |
| SCHEMBL24197084 | 0.61 | — | — | |
| SCHEMBL3941614 | 0.60 | — | — | |
| SCHEMBL15427286 | 0.59 | — | — | |
| SCHEMBL10050813 | 0.59 | — | — | |
| SCHEMBL13798795 | 0.57 | — | — | |
| SCHEMBL25469670 | 0.57 | — | — | |
| SCHEMBL8925523 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072795-A1 | ELECTRONIC SWITCHING DEVICE | MERCK PATENT GMBH (DE) | 2023-05-04 | — | — | WO | disclosed |
| WO-2016196244-A1 | PYRIDINEAMINE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | INCYTE CORPORATION (US) | 2016-12-08 | — | — | WO | disclosed |
| EP-2945939-A1 | THIAZOLECARBOXAMIDES AND PYRIDINECARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | Incyte Corporation (US) | 2015-11-25 | — | — | EP | disclosed |
| CN-105051029-A | Thiazolecarboxamide and picolinamide compounds useful as PIM kinase inhibitors | INCYTE CORP | 2015-11-11 | — | — | CN | disclosed |
| WO-2014113388-A1 | THIAZOLECARBOXAMIDES AND PYRIDINECARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | INCYTE CORPORATION (US) | 2014-07-24 | — | — | WO | disclosed |