⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2276275 | 0.91 | — | — | |
| SCHEMBL14355410 | 0.84 | — | — | |
| SCHEMBL12163166 | 0.84 | — | — | |
| SCHEMBL4223261 | 0.78 | — | — | |
| SCHEMBL25449999 | 0.76 | — | — | |
| SCHEMBL16878438 | 0.75 | — | — | |
| SCHEMBL24024127 | 0.75 | — | — | |
| SCHEMBL1636208 | 0.75 | — | — | |
| SCHEMBL16878430 | 0.73 | — | — | |
| SCHEMBL16878740 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10028942-B2 | 3-substituted pyrazoles and uses thereof | GENENTECH, INC. (US) | 2018-07-24 | — | — | US | claimed |
| EP-2945938-B1 | 3-SUBSTITUTED PYRAZOLES AND USE AS DLK INHIBITORS | HOFFMANN LA ROCHE (CH) | 2018-03-07 | — | — | EP | claimed |
| US-20170087137-A1 | 3-SUBSTITUTED PYRAZOLES AND USES THEREOF | GENENTECH, INC. (US) | 2017-03-30 | — | — | US | claimed |
| US-9550777-B2 | 3-substituted pyrazoles and use as DLK inhibitors | GENENTECH, INC. (US) | 2017-01-24 | — | — | US | claimed |
| US-20160002228-A1 | 3-SUBSTITUTED PYRAZOLES AND USE AS DLK INHIBITORS | GENENTECH, INC. (US) | 2016-01-07 | — | — | US | claimed |
| EP-2945938-A1 | 3-SUBSTITUTED PYRAZOLES AND USE AS DLK INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2015-11-25 | — | — | EP | claimed |
| WO-2014111496-A1 | 3-SUBSTITUTED PYRAZOLES AND USE AS DLK INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2014-07-24 | — | — | WO | claimed |
| WO-2026093741-A1 | HETERO-[3.1.1]PROPELLANE COMPOUNDS, SYNTHESIS AND USES THEREOF | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2026-05-07 | — | — | WO | disclosed |
| EP-4695238-A1 | CDK2 INHIBITORS | Blueprint Medicines Corporation (US) | 2026-02-18 | — | — | EP | disclosed |
| EP-4646411-A1 | CDK2 INHIBITORS | Blueprint Medicines Corporation (US) | 2025-11-12 | — | — | EP | disclosed |
| EP-4646414-A1 | CDK2 INHIBITORS | Blueprint Medicines Corporation (US) | 2025-11-12 | — | — | EP | disclosed |
| EP-4646416-A1 | CDK2 INHIBITORS | Blueprint Medicines Corporation (US) | 2025-11-12 | — | — | EP | disclosed |
| CN-120136870-A | GLP-1 receptor targeting compounds and uses thereof | 信达生物科技有限公司 | 2025-06-13 | — | — | CN | disclosed |
| US-20160297826-A1 | TYK2 INHIBITORS AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-10-13 | — | — | US | disclosed |
| US-9340540-B2 | TYK2 inhibitors and uses thereof | NIMBUS LAKSHMI, INC. (US) | 2016-05-17 | — | — | US | disclosed |
| US-20160002228-A1 | 3-SUBSTITUTED PYRAZOLES AND USE AS DLK INHIBITORS | GENENTECH, INC. (US) | 2016-01-07 | — | — | US | disclosed |
| EP-2945938-A1 | 3-SUBSTITUTED PYRAZOLES AND USE AS DLK INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2015-11-25 | — | — | EP | disclosed |
| US-20150266875-A1 | TYK2 INHIBITORS AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-09-24 | — | — | US | disclosed |
| WO-2015103583-A1 | MONOBACTAMS AND METHODS OF THEIR SYNTHESIS AND USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-07-09 | — | — | WO | disclosed |
| WO-2014111496-A1 | 3-SUBSTITUTED PYRAZOLES AND USE AS DLK INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2014-07-24 | — | — | WO | disclosed |